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The worlds top protection agent [Ryan Reynolds] is called upon to guard the life of his mortal enemy, one of the worlds most notorious hitmen [Samuel L. Jackson]. The relentless bodyguard and manipulative assassin have been on the opposite end of the bullet for years and are thrown together for a wildly outrageous 24 hours. During their raucous and hilarious adventure from England to the Hague, they encounter high-speed car chases, outlandish boat escapades and a merciless Eastern European dictator [Gary Oldman] who is out for blood. Salma Hayek joins the mayhem as Jacksons equally notorious wife.